Fatty Acids, Nonesterified
Research News and Information

Sunday, November 22, 2009

Flip-flop is the rate-limiting step for transport of free fatty acids across lipid vesicle membranes.

Nov 2009 The mechanism of transport of free fatty acids (FFA) across lipid bilayer membranes remains a subject of debate. The debate is whether the rate-limiting step for transport is flip-flop across the membrane or dissociation into the aqueous phase. ... Read more...

Serum levels of interleukin-18 are reduced by diet and n-3 fatty acid intervention in elderly high-risk men.

30 Oct 2009 Inflammation plays a central role in the development and progression of atherosclerosis, and inflammatory markers have been reported to predict cardiovascular events. Mediterranean-like diet and very long chain omega-3 polyunsaturated fatty acid ... Read more...

The adrenergic-fatty acid load in heart failure.

25 Oct 2009 The hypothesis proposed is that heart failure (HF) is associated with a reactive hyperadrenergic state that increases circulating plasma free fatty acids (FFAs), which leads to impaired glucose metabolism and insulin resistance. We propose that ... Read more...

Latest indexed articles for 'Fatty Acids, Nonesterified'

These are the very latest articles for this heading:

• Flip-flop is the rate-limiting step for transport of free fatty acids across lipid vesicle membranes. Nov 2009
• Serum levels of interleukin-18 are reduced by diet and n-3 fatty acid intervention in elderly high-risk men. 30 Oct 2009
• The adrenergic-fatty acid load in heart failure. 25 Oct 2009
• Variation of meat quality traits among five genotypes of chicken. 29 Sep 2009
• Transport stress in broilers: I. Blood metabolism, glycolytic potential, and meat quality. 29 Sep 2009
• Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis. 29 Sep 2009
• Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. 29 Sep 2009
• Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha. 29 Sep 2009
• Regulation of ANKRD9 expression by lipid metabolic perturbations. 28 Sep 2009
• Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability. 21 Sep 2009
• A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes without affecting development of heart failure with pressure overload. 16 Sep 2009
• Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4. 12 Sep 2009
• Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice. 10 Sep 2009
• Ceramide mediates inhibition of the AKT/eNOS signaling pathway by palmitate in human vascular endothelial cells. 30 Aug 2009
• High protein intake reduces intrahepatocellular lipid deposition in humans. 24 Aug 2009
• Free fatty acid-induced muscle insulin resistance and glucose uptake dysfunction: evidence for PKC activation and oxidative stress-activated signaling pathways. 21 Aug 2009
• Reduction of renal triglyceride accumulation: effects on proximal tubule Na+/H+ exchange and urinary acidification. 17 Aug 2009
• UCP3 expression in liver modulates gene expression and oxidative metabolism in response to fatty acids, and sensitizes mitochondria to permeability transition. Aug 2009
• Acyl hydroxypyrazoles as novel agonists for high-affinity nicotinic acid receptor GPR109A: WO2008051403. 30 Jul 2009
• Treatment of hypertension in metabolic syndrome subjects with amlodipine and olmesartan-effects on oxidized non-esterified free fatty acids and cytokine production. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Fatty Acids, Nonesterified'

Definition: FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.

Registry Number: 0

Descriptor UI: D005230

Alternative terms: Fatty Acids, Nonesterified; Acids, Nonesterified Fatty; Nonesterified Fatty Acids; Free Fatty Acids; NEFA; Fatty Acids, Free; Acids, Free Fatty;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D10.251.310;

History Note: 68(66)

Technical Notes: DF: note short X ref