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| Research article summary (published 27 Feb 2009): |
Comparative study of children with ADHD only, autism spectrum disorder + ADHD, and chronic multiple tic disorder + ADHD.
Full Abstract
OBJECTIVE: Identification of differences among children with ADHD only, autism spectrum disorder (ASD)+ADHD, and chronic multiple tic disorder (CMTD)+ADHD may lead to better understanding of clinical phenotypes. METHOD: Children were evaluated using the parent- and teacher-completed questionnaires. RESULTS: All three groups were highly similar in severity of oppositional defiant disorder and conduct disorder symptoms; however, the ASD+ADHD group generally exhibited the most severe anxiety, although the CMTD+ADHD group had the most severe generalized anxiety. The two comorbid groups had the most involved medical histories and the greatest likelihood of a family history of psychopathology. CONCLUSION: Groups differed in clinically meaningful ways, and the apparent association between tics and anxiety may explain in part the elevated levels of anxiety in both comorbid groups. Collectively, results suggest that ADHD may be better conceptualized as a family of interrelated syndromes defined in part by comorbid conditions and that continued research is clearly warranted.
Author information
Author/s: Gadow, Kenneth D (KD); DeVincent, Carla J (CJ); Schneider, Jayne (J);
Affiliation: Department of Psychiatry and Behavioral Science, State University of New York at Stony Brook, Stony Brook, NY 11794-8790, USA. kdgadow(-atsign-)notes.cc.sunysb.edu
Grants: MH 45358 (Agency:NIMH NIH HHS)
Journal and publication information
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal: Journal of attention disorders (J Atten Disord), published in United States. (Language: eng)
Reference: 2009-Mar; vol 12 (issue 5) : pp 474-85
Dates: Created 2009/02/16; Completed 2009/05/11;
PMID: 19218544, status: MEDLINE (last retrieval date: 5/11/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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