Research article summary (published 30 May 2009):

Depression and cognitive complaints following mild traumatic brain injury.

Full Abstract

Traumatic brain injury (TBI) is a common occurrence with multiple possible neuropsychiatric sequelae, including problems with cognition, emotion, and behavior. While many individuals experience significant improvement over the first months following mild TBI, a nontrivial minority will develop persistent, functionally impairing post-TBI symptoms. Depression and cognitive impairment are among the most common such symptoms, and they may respond to a combination of rehabilitative and pharmacologic treatments. This article discusses the clinical approach to treating an individual with depression and cognitive complaints following mild TBI. Recommendations regarding the diagnosis, evaluation, and treatment of these problems are offered.

Author information

Author/s: Silver, Jonathan M (JM); McAllister, Thomas W (TW); Arciniegas, David B (DB);

Affiliation: Department of Psychiatry, New York University, New Yourk, NY, USA. jonsilver(-atsign-)gmail.com

Grants: R01 HD048176-01 (Agency:NICHD NIH HHS) ; R01 NS055020 (Agency:NINDS NIH HHS) ; R01 NS40472-01 (Agency:NINDS NIH HHS) ; R01HD48638 (Agency:NICHD NIH HHS)

Journal and publication information

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

Journal: The American journal of psychiatry (Am J Psychiatry), published in United States. (Language: eng)

Reference: 2009-Jun; vol 166 (issue 6) : pp 653-61

Dates: Created 2009/06/02; Completed 2009/06/30;

PMID: 19487401, status: MEDLINE (last retrieval date: 6/30/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Antidepressive Agents, Tricyclic - adverse effects; therapeutic use Brain - anatomy & histology; physiopathology Brain Injuries - complications; physiopathology Central Nervous System Stimulants - therapeutic use Choline - antagonists & inhibitors Citalopram - adverse effects; therapeutic use Cognition Disorders - diagnosis; etiology; therapy Cognitive Therapy - methods

Cognitive Therapy - methods Depression - diagnosis; drug therapy; etiology Humans Methylphenidate - therapeutic use Neuropsychological Tests Serotonin Uptake Inhibitors - therapeutic use Sertraline - adverse effects; therapeutic use Severity of Illness Index

Associated Chemicals: Antidepressive Agents, Tricyclic (0) ; Central Nervous System Stimulants (0) ; Serotonin Uptake Inhibitors (0) ; Methylphenidate (113-45-1) ; Citalopram (59729-33-8) ; Choline (62-49-7) ; Sertraline (79617-96-2)

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