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| Research article summary (published 30 May 2009): |
Prevalence and sex differences of psychiatric disorders in young adults who had intermittent exotropia as children.
Full Abstract
OBJECTIVE: To evaluate the prevalence and sex differences of mental disorders diagnosed among young adults who had intermittent exotropia (IXT) as children. METHODS: The medical records of all children (<19 years) diagnosed as having IXT as residents of Olmsted County, Minnesota, from January 1, 1975, through December 31, 1994, and their randomly selected nonstrabismic birth- and sex-matched controls (1:1) were retrospectively reviewed. RESULTS: A mental health disorder was diagnosed in 97 (53.0%) of the 183 patients with childhood IXT followed to a mean age of 22 years compared with 55 (30.1%) controls (P < .001). Patients with IXT were 2.7 (95% confidence interval, 1.7-4.1) times more likely to develop a psychiatric illness than controls. A mental health disorder was diagnosed in 63% (41 of 65) and 47% (56 of 118) of males and females with IXT, respectively, compared with 33% (22 of 66) and 28% (33 of 117) of male and female controls, respectively. Additionally, males with IXT had a greater use of psychotropic medication (P = .003), psychiatric emergency department visits (P < .001), psychiatric hospital admissions (P = .04), suicide attempts (P = .004), and suicidal ideation (P = .002) than controls, and females with IXT had more suicidal ideation (P = .02) than controls. CONCLUSIONS: Children diagnosed as having IXT, especially males, are more likely to develop mental illness by the third decade of life compared with children without strabismus.
Author information
Author/s: McKenzie, Jeff A (JA); Capo, Jason A (JA); Nusz, Kevin J (KJ); Diehl, Nancy N (NN); Mohney, Brian G (BG);
Affiliation: College of Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: Archives of ophthalmology (Arch Ophthalmol), published in United States. (Language: eng)
Reference: 2009-Jun; vol 127 (issue 6) : pp 743-7
Dates: Created 2009/06/09; Completed 2009/06/26; Revised 2009/10/19;
PMID: 19506192, status: MEDLINE (last retrieval date: 10/20/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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