Research article summary (published 30 Oct 2009):

TLR2 joins the interferon gang.

Full Abstract

The induction of type I interferon is a critical checkpoint in antiviral immunity. Toll-like receptor 2 can unexpectedly induce type I interferon in the subset of inflammatory monocytes during infection with vaccinia virus.

Author information

Author/s: Bauernfeind, Franz (F); Hornung, Veit (V);

Journal and publication information

Publication Type: Comment; News

Journal: Nature immunology (Nat Immunol), published in United States. (Language: eng)

Reference: 2009-Nov; vol 10 (issue 11) : pp 1139-41

Dates: Created 2009/10/20; Completed 2009/10/23;

PMID: 19841644, status: MEDLINE (last retrieval date: 10/23/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

Comments and Corrections

CommentOn: Nat Immunol. 2009 Nov;10(11):1200-7. (PMID: 19801985)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Animals Interferon Type I - immunology; metabolism Mice Monocytes - immunology

Monocytes - immunology Toll-Like Receptor 2 - immunology; metabolism Vaccinia - immunology Vaccinia virus - immunology

Associated Chemicals: Interferon Type I (0) ; Tlr2 protein, mouse (0) ; Toll-Like Receptor 2 (0)

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